Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp15 | Arthritis and other joint diseases: translational and clinical | ECTS2013

Cartilage intermediate layer protein is produced in synovial membrane of osteoarthritic joint and upregulated in osteoarthritis associated fibrosis

Kerna Irina , Kisand Kalle , Tamm Ann , Tamm Agu

Introduction: Cartilage intermediate layer protein (CILP) is a promising marker of osteoarthritis (OA). CILP is an extracellular matrix glycoprotein, which is produced by cartilage chondrocytes. Still, there are data that CILP could be found also in other tissues. We aimed to investigate the expression level of CILP mRNA in the synovial membrane and evaluated the associations of CILP expression with traits of radiographic knee OA (rKOA) and features of histol...